HOMA-IR Formula:
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HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function from fasting blood glucose and insulin levels.
The calculator uses the HOMA-IR formula:
Where:
Explanation: The formula provides a simple way to estimate insulin resistance using fasting blood measurements.
Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with various metabolic disorders including type 2 diabetes, metabolic syndrome, and cardiovascular disease.
Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.
Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest significant insulin resistance.
Q2: When should HOMA-IR testing be done?
A: Testing should be performed after an overnight fast of 8-12 hours for accurate results.
Q3: Are there limitations to HOMA-IR?
A: While useful for population studies, HOMA-IR may not be as accurate as more sophisticated tests like hyperinsulinemic-euglycemic clamp for individual assessment.
Q4: Can HOMA-IR be used to diagnose diabetes?
A: HOMA-IR assesses insulin resistance but is not a diagnostic tool for diabetes. Diagnosis should be based on established criteria including fasting glucose and HbA1c levels.
Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context. Generally, it's measured as part of metabolic health assessments or when monitoring treatment response.